Gli1 Expression in Human Epiretinal Membranes
نویسندگان
چکیده
منابع مشابه
Aquaporin-1 Expression in Proliferative Vitreoretinopathy and in Epiretinal Membranes
PURPOSE Aquaporin-1 (AQP1) is involved in cell migration and proliferation; therefore, the purpose of the study was to investigate its expression in proliferative vitreoretinopathy (PVR) and epiretinal membranes (ERM). METHODS 19 membranes from PVR and ERM were collected following eye surgery. AQP1 mRNA and protein expressions were determined by RT-qPCR and immunofluorescence in the membranes...
متن کاملGanglion cell neurites in human idiopathic epiretinal membranes.
AIM To identify and confirm the presence of neural elements in idiopathic epiretinal membranes removed from patients' eyes during vitrectomy with epiretinal membrane peeling. METHODS Human epiretinal membranes from patients with no other known eye disease and of varying durations were labelled immunohistochemically with antibodies for neurofilament protein, laminin and either vimentin or GFAP...
متن کاملNeurotrophic factor receptors in epiretinal membranes after human diabetic retinopathy.
OBJECTIVE Formation of epiretinal membranes (ERMs) in the posterior fundus results in progressive deterioration of vision. ERMs have been associated with numerous clinical conditions, including proliferative diabetic retinopathy (PDR), but its pathogenic mechanisms are still unknown. This study was conducted to determine whether neurotrophic factor receptors (tyrosine kinase receptors trkA, trk...
متن کاملDiverse NF-kappaB expression in epiretinal membranes after human diabetic retinopathy and proliferative vitreoretinopathy.
PURPOSE Formation of epiretinal membranes (ERMs) after proliferative diabetic retinopathy (PDR) and proliferative vitreoretinopathy (PVR) results in progressive deterioration of vision, but its pathogenic mechanisms are still unknown. This study was conducted to examine the role of nuclear factor kappa B (NF-kappaB) in the formation of ERMs after PDR and PVR. METHODS ERM samples were obtained...
متن کاملComparison of Gene Expression Profile of Epiretinal Membranes Obtained from Eyes with Proliferative Vitreoretinopathy to That of Secondary Epiretinal Membranes
BACKGROUND Proliferative vitreoretinopathy (PVR) is a destructive complication of retinal detachment and vitreoretinal surgery which can lead to severe vision reduction by tractional retinal detachments. The purpose of this study was to determine the gene expression profile of epiretinal membranes (ERMs) associated with a PVR (PVR-ERM) and to compare it to the expression profile of less-aggress...
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ژورنال
عنوان ژورنال: Investigative Opthalmology & Visual Science
سال: 2017
ISSN: 1552-5783
DOI: 10.1167/iovs.16-20409